The knowledge traditions of Salish country are neither old fashioned nor out of date. Indeed, this body of knowledge collected in the people, stories, songs, and the land has the most modern application: prevention and treatment of chronic diseases that now afflict growing numbers of native peoples as well as non- natives living in Salish country. We use “Salish country” to identify a region of coastal northwest United States and southwest Canada and parts of their interior where peoples as similar and different as the Wuikinuxv, Wenatchee, Semiamoo, Skagit, Quinault, Clatsop, and Siletz live. What these peoples and their immediate neighbors share are rivers and other water pathways connecting them and languages rooted in what the linguists call Salish. These connections fostered cultural ties that have existed over the millenia and to the present day.